Our ability to cheaply and quickly sequence DNA is transforming healthcare. Genomics unlocks new tools for researchers to understand diseases and develop effective treatments. It allows doctors to diagnose rare conditions, explore the genetic roots of their patients’ health, and customize treatments to patients’ individual genetic profiles. As genomics is integrated throughout the medical field, a world of personalized medicine is emerging. To understand what this future holds, we collaborated with academics, researchers, and clinicians for a series of articles on genomic medicine.